In this application spotlight, a team of researchers from the Baker Heart and Diabetes Institute in Melbourne,
Australia, report on a special type of activated platelet that accumulate locally within cancer tumors that
provide molecular imaging capabilities. scFvGPIIB/IIa (the biomolecule) has been conjugated to Cy7 (the
fluorescent dye), which then binds to a receptor on activated platelets that are expressed in cancer cells.
The researchers implanted xenograft tumors in mice to assess performance of the probe in vivo