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In this application spotlight, a team of researchers from the Baker Heart and Diabetes Institute in Melbourne,

Australia, report on a special type of activated platelet that accumulate locally within cancer tumors that
provide molecular imaging capabilities. scFvGPIIB/IIa (the biomolecule) has been conjugated to Cy7 (the
fluorescent dye), which then binds to a receptor on activated platelets that are expressed in cancer cells.

The researchers implanted xenograft tumors in mice to assess performance of the probe in vivo

 

Link: http://dx.doi.org/10.7150/thno.19900