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Improved management of hepatitis D

fusion spectra


HDV is a small, defective RNA virus that can infect only individuals who have HBV; worldwide
more than 15 million people are co-infected. HDV increases the severity of chronic HBV infection,
frequently leading to cirrhosis, hepatic decompensation or hepatocellular carcinoma. The prevalence
of HDV is declining in some endemic areas but increasing in northern and central Europe
because of immigration. Interferon-alpha is currently the only available treatment option leading
to suppression of HDV RNA in 25 % - 30 % of patients [

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